File:5b16 drosha dgcr8.png
From Vigyanwiki
Size of this preview: 350 × 600 pixels. Other resolutions: 140 × 240 pixels | 280 × 480 pixels | 700 × 1,200 pixels.
Original file (700 × 1,200 pixels, file size: 617 KB, MIME type: image/png)
Summary
| Description |
English: The crystal structure of the human Drosha ribonuclease enzyme in complex with two C-terminal helices of the DGCR8 protein. Drosha is shown with its two ribonuclease III domains in blue and orange, its double-stranded RNA binding domain in yellow, and the remainder of the protein, including two bound zinc ions (spheres) in gray. DGCR8 helices are shown in green. (Note: DGCR8 is also known as Pasha, or Partner of Drosha, in flies and worms.) Together, Drosha and DGCR8 form the Microprocessor complex, responsible for the processing of primary microRNA to pre-miRNA in the nucleus of almost all animal cells, the first step for producing endogenously derived miRNA involved in RNA interference. Rendered using PyMol from PDB ID 5A16. |
| Date | |
| Source | Own work |
| Author | Opabinia regalis |
Licensing
I, the copyright holder of this work, hereby publish it under the following licences:
This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported licence.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the licence, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible licence as the original.
|
Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation Licence, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the licence is included in the section entitled GNU Free Documentation Licence. |
You may select the licence of your choice.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 07:07, 17 February 2016 | | 700 × 1,200 (617 KB) | wikimediacommons>Opabinia regalis | {{Information |Description ={{en|1=The crystal structure of the human Drosha ribonuclease enzyme in complex with two C-terminal helices of the DCGR8 protein. Drosha is shown with its two ribonuclease III domains in blue and orange, its double-strand... |
File usage
The following 2 pages use this file:
