English: a) The simplest case of saturation kinetics extends from the pre-equilibrium situation in which rapid substrate complexation with a catalyst is followed by slow formation of the product. b) The straight line for substrate concentration over time is indicative of a zero-order dependence on substrate for most of the reaction. c) Saturation of the catalyst is apparent at high concentrations of substrate (where the rate has no dependence on [A], but as substrate is consumed, the reaction rate drops with a first-order dependence on [A] to pass through the origin. d) The catalyst resting state is further indicative of saturation, as the catalyst exists almost entirely as the substrate-bound complex at high [A]. The data used to generate these plots were obtained by kinetic simulations with CopasiIU free software using the arbitrary rate constants K1=k1/k-1=100/5 and k2= 1 (1/s)